Proceedings

Qualitative Simulation of Genetic Regulatory Networks: Method and Application

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Proceedings of the Seventeenth International Joint Conference on Artificial Intelligence. Pages 67-72.

Abstract

Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simulation of large and complex genetic regulatory networks. The method allows a broad range of regulatory interactions between genes to be represented and has been applied to the analysis of a real network of biological interest, the network controlling the inititation of sporulation in the bacterium B. subtilis.

Hidde de Jong, Michel Page, Céline Hernandez, and Johannes Geiselmann. 2001. Qualitative Simulation of Genetic Regulatory Networks: Method and Application. In Proceedings of the Seventeenth International Joint Conference on Artificial Intelligence, IJCAI-01. IJCAI, 67–72. https://ijcai.org/proceedings/2001/9
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