Discrimination of Semi-Quantitative Models by Experiment Selection: Method and Application in Population Biology

Vatcheva, Ivayla; Bernard, Olivier; de Jong, Hidde; Gouzé, Jean-Luc; Mars, Nicolaas J. I.

Discrimination of Semi-Quantitative Models by Experiment Selection: Method and Application in Population Biology

Ivayla Vatcheva, Olivier Bernard, Hidde de Jong, Jean-Luc Gouzé, Nicolaas J. I. Mars

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Proceedings of the Seventeenth International Joint Conference on Artificial Intelligence. Pages 74-81.

Abstract

Modeling an experimental system often results in a number of alternative models that are justified equally well by the experimental data. In order to discriminate between these models, additional experiments are needed. We present a method for the discrimination of models in the form of semiquantitative differential equations. The method is a generalization of previous work in model discrimination. It is based on an entropy criterion for the selection of the most informative experiment which can handle cases where the models predict multiple qualitative behaviors. The applicability of the method is demonstrated on a real-life example, the discrimination of a set of competing models of the growth of phytoplankton in a bioreactor.

Ivayla Vatcheva, Olivier Bernard, Hidde de Jong, Jean-Luc Gouzé, and Nicolaas J. I. Mars. 2001. Discrimination of Semi-Quantitative Models by Experiment Selection: Method and Application in Population Biology. In Proceedings of the Seventeenth International Joint Conference on Artificial Intelligence, IJCAI-01. IJCAI, 74–81. https://ijcai.org/proceedings/2001/10

@inproceedings{ijcai2001p10,
  title     = {Discrimination of Semi-Quantitative Models by Experiment Selection: Method and Application in Population Biology},
  author    = {Vatcheva, Ivayla and Bernard, Olivier and de Jong, Hidde and Gouzé, Jean-Luc and Mars, Nicolaas J. I.},
  booktitle = {Proceedings of the Seventeenth International Joint Conference on
               Artificial Intelligence, {IJCAI-01}},
  publisher = {International Joint Conferences on Artificial Intelligence},
  pages     = {74--81},
  year      = {2001},
  url       = {https://ijcai.org/proceedings/2001/10},
}

TY  - CPAPER
TI  - Discrimination of Semi-Quantitative Models by Experiment Selection: Method and Application in Population Biology
AU  - Vatcheva, Ivayla
AU  - Bernard, Olivier
AU  - de Jong, Hidde
AU  - Gouzé, Jean-Luc
AU  - Mars, Nicolaas J. I.
T2  - Proceedings of the Seventeenth International Joint Conference on Artificial Intelligence, IJCAI-01
PB  - International Joint Conferences on Artificial Intelligence
PY  - 2001
SP  - 74
EP  - 81
UR  - https://ijcai.org/proceedings/2001/10
ER  -