{"type":"ScholarlyArticle","title":"Representation of Empirically Derived Causal Relationships","authors":[{"name":"Robert L. Blum","slug":"robert-l-blum","given":"Robert L.","family":"Blum","affiliation":"Department of Computer Science Stanford University Stanford , California 94305"}],"abstract":"The objective of this paper is to present a method for the computer representation of empirically derived causal relationships (CR's). This method draws on the theory of multivariate linear models and path analysis. The method is contrasted with the predicate calculus based methods used by most researchers in artificial intelligence. The representation presented here has been used to store information on medical CR's derived empirically from a large clinical database by a computer program called RX. The principal emphasis in the representation is on capturing the intensities and variances of effects and the variation in the effects across a patient population. Once incorporated into RX's knowledge base, this information is subsequently used by RX in determining the validity of other CR's. The representation uses a directed graph formalism in which the nodes are frames and the arcs contain seven descriptive features of individual CR's: intensity, distribution, direction, mathematical form, setting, validity, and evidence. Because natural systems (such as the human body) are inherently probabilistic, linear models are useful in representing causal flow in them. Knowledge of natural systems is fundamentally probabilistic because of 1) irreducible indeterminism in their component processes, 2) difficulties in accurately measuring all relevant variables, 3) variation among individuals in a population, and 4) inadequate scientific theory. The principal objective of this paper is to present a method for the computer representation of causal relationships relevant to clinical medlClne. The representation presented here is used to store information on clinical causal relationships in the medical knowledge base of a large computer program called RX. In this brief report I will touch on the following topics: 1) the objectives and methods of the RX Project, 2) the characteristics of the tasks that RX performs that influence the admissible forms of representation for causal relationships, 3) the method of representation, and 4) a comparison of this method with the work of other AI researchers.","doi":null,"url":"https://ijcai.org/proceedings/1983/66","pdf":"https://ijcai.org/proceedings/1983/0066.pdf","markdown":"https://ijcai.org/proceedings/1983/66.md","bibtex":"https://ijcai.org/proceedings/1983/bibtex/66","volume":{"slug":"1983","title":"Proceedings of the Eighth International Joint Conference on Artificial Intelligence","short_title":"IJCAI 1983","url":"https://ijcai.org/proceedings/1983/","year":1983,"location":"Karlsruhe, West Germany","dates":"","editors":"Alan Bundy","isbn":"","publisher":"International Joint Conferences on Artificial Intelligence","doi_prefix":""},"section":"Expert Systems","track":"Expert Systems","number":66,"pages":{"first":268,"last":270},"keywords":[],"videos":[],"references":[{"position":1,"raw":"Bentler, P.M., Multivariate Analysis with Latent Variables: Causal Modeling; Annual Reviews of Psychology 31:419-456, 1980.","title":"Multivariate Analysis with Latent Variables: Causal Modeling","authors":"P M Bentler","year":"1980","venue":"Annual Reviews of Psychology","doi":null,"url":null,"internal_url":null},{"position":2,"raw":"1982a] Blum, R.L., Discovery and Representa- tion of Causal Relationships from a Large Time- Oriented Database: The RX Project; A monograph in the Medical Informatics Series, edited by D. Lindberg and P.Reichertz, Springer-Verlag, 1982.","title":"Discovery and Representation of Causal Relationships from a Large Time-Oriented Database: The RX Project","authors":"R L Blum","year":"1982","venue":"A monograph in the Medical Informatics Series","doi":null,"url":null,"internal_url":null},{"position":3,"raw":"1982b] Blum, R.L., Discovery, Confirmation, and Incorporation of Causal Relationships from a Large Time-Oriented Database: The RX Project; Computers and Biomedical Research 15:164-187, 1982.","title":"Discovery, Confirmation, and Incorporation of Causal Relationships from a Large Time-Oriented Database: The RX Project","authors":"R L Blum","year":"1982","venue":"Computers and Biomedical Research","doi":null,"url":null,"internal_url":null},{"position":4,"raw":"de Kleer 1981]","title":null,"authors":"De Kleer","year":"1981","venue":null,"doi":null,"url":null,"internal_url":null},{"position":5,"raw":"de Kleer,J. and Brown,J.S., Mental Models of Physical Mechanisms and Their Acquisi- tion; in John Anderson (ed.), Cognitive Skills and Their Acquisition, Erlbaum, 1981.","title":"Mental Models of Physical Mechanisms and Their Acquisition","authors":"J De Kleer, J S Brown","year":"1981","venue":"Cognitive Skills and Their Acquisition","doi":null,"url":null,"internal_url":null},{"position":6,"raw":"Fries,J.F. and McShane,D.J., ARAMIS: A National Chronic Disease Data Bank System; in Proc. of the 3rd Annual Symp. on Computer Appli- cations in Medical Care, pp. 798-801, IEEE, Washington,D.C., Oct., 1979.","title":"ARAMIS: A National Chronic Disease Data Bank System","authors":"J F Fries, D J Mcshane","year":"1979","venue":"Proc. of the 3rd Annual Symp. on Computer Applications in Medical Care","doi":null,"url":null,"internal_url":null},{"position":7,"raw":"Heise 1975","title":null,"authors":"Heise","year":"1975","venue":null,"doi":null,"url":null,"internal_url":null},{"position":8,"raw":"Heise,D., Path Analysis; John Wiley & Sons, 1975.","title":"Path Analysis","authors":"D Heise","year":"1975","venue":null,"doi":null,"url":null,"internal_url":null},{"position":9,"raw":"Kenny 1979","title":null,"authors":"Kenny","year":"1979","venue":null,"doi":null,"url":null,"internal_url":null},{"position":10,"raw":"Kenny,D., Correlation and Causality; John Wiley & Co., 1979.","title":"Correlation and Causality","authors":"D Kenny","year":"1979","venue":null,"doi":null,"url":null,"internal_url":null},{"position":11,"raw":"McShane 1979]","title":null,"authors":"Mcshane","year":"1979","venue":null,"doi":null,"url":null,"internal_url":null},{"position":12,"raw":"McShane,D.J., Harlow,A., Kraines, R.G., and Fries,J.F., TOD: A Software System for the ARAMIS Data Bank; Computer 12:34-40, Nov. 1979.","title":"A Software System for the ARAMIS Data Bank","authors":"D J Mcshane, A Harlow, R G Kraines, J F Fries","year":"1979","venue":"Computer","doi":null,"url":null,"internal_url":null},{"position":13,"raw":"Rieger,C. and Grinberg,M., The Dec- larative Representation and Procedural Simula- tion of Causality in Physical Mechanisms; in Proc. of the 5th International Joint Conference on Artificial Intelligence, pp.250-255, IJCAI 1977. .","title":"The Declarative Representation and Procedural Simulation of Causality in Physical Mechanisms","authors":"C Rieger, M Grinberg","year":"1977","venue":"Proc. of the 5th International Joint Conference on Artificial Intelligence","doi":null,"url":null,"internal_url":"/proceedings/1977/55"},{"position":14,"raw":"Rieger,C. and Grinberg,M., A System of Cause-Effect Representation and Simulation for Computer-Aided Design; in Latombe (ed.), Artificial Intelligence and Pattern Recognition in Computer-Aided Design, pp.299-326, North- Holland, 1978.","title":"A System of Cause-Effect Representation and Simulation for Computer-Aided Design","authors":"C Rieger, M Grinberg","year":"1978","venue":"Artificial Intelligence and Pattern Recognition in Computer-Aided Design","doi":null,"url":null,"internal_url":null},{"position":15,"raw":"Suppes,P., A probabilistic Theory of Causality, North-Holland Publishing Co., Amster- dam, 1970.","title":"A probabilistic Theory of Causality","authors":"P Suppes","year":"1970","venue":null,"doi":null,"url":null,"internal_url":null},{"position":16,"raw":"Szolovits 1982","title":null,"authors":"Szolovits","year":"1982","venue":null,"doi":null,"url":null,"internal_url":null},{"position":17,"raw":"Szolovits,P. (ed.), Artificial Intelligence in Medicine; Westview Press, Boulder, Colorado, 1982.","title":"Artificial Intelligence in Medicine","authors":null,"year":"1982","venue":null,"doi":null,"url":null,"internal_url":null}],"license_note":"Copyright International Joint Conferences on Artificial Intelligence."}